关键词: 淋巴瘤, 非霍奇金, 药物疗法, 放射疗法, 分子靶向治疗

Abstract: As recent researches suggested, the continuous infusion and novel targeted medicines have been expected to improve the outcome of patients with aggressive B-cell non-Hodgkin's lymphoma. Nevertheless, it does not shown to improve the curative effect by increasingly intensive dosage. Patients with aggressive T-cell non-Hodgkin's lymphoma have present better prognosis recently, which attributed to better efficacy of the modified regimens in patients with NK/T cell lymphoma. Multiple genetic abnormalities are implicated in poorer prognosis in patients with aggressive T-cell non-Hodgkin's lymphoma. Non-myeloablative allogeneic stem cell transplantation and new targeted drugs have showed to improve the curative effects. Radiotherapy with modern technology also is expected to become an important means to improve outcomes of aggressive non-Hodgkin's lymphoma.

Key words: Lymphoma, non-Hodgkin, Drug therapy, Radiotherapy, Molecular targeted therapy