国际肿瘤学杂志

国际肿瘤学杂志 ›› 2013, Vol. 40 ›› Issue (5): 323-325.

• 综述 •    下一篇

骨形态发生蛋白与肿瘤

米东, 张月香, 陈淑琴, 祁珮   

  1. 作者单位：300100天津市中心妇产科医院检验科
  • 出版日期:2013-05-08 发布日期:2013-05-15

Bone morphogenetic proteins and tumors

米东，张月香，陈淑琴，祁珮   

  1. Department of Clinical Laboratory, Tianjin Central Hospital of Obstetrics and Gynecology, Tianjin 300100, China
  • Online:2013-05-08 Published:2013-05-15

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摘要： 骨形态发生蛋白（BMP）是一种多功能的细胞因子，不仅可以促进新骨形成，而且参与调控细胞生长、分化、迁移、凋亡以及胚胎和器官发生等过程。研究显示BMP还与肿瘤的发生和转移密切相关，在肿瘤治疗中具有重要的应用价值。

关键词: 骨形态发生蛋白质类, 肿瘤, 治疗

Abstract: Bone morphogenetic proteins are multi-functional growth factors, they are found not only inducer of new bone formation, but also have critical roles in cell growth, differentiation, migration, apoptosis, embryogenesis and organogenesis. Studies show that BMPs are closely related to tumorigenesis and metastasis, which indicate that BMPs have important practical values in tumour therapy.

Key words: Bone morphogenetic proteins, Neoplasms, Therapy