国际肿瘤学杂志

国际肿瘤学杂志 ›› 2012, Vol. 39 ›› Issue (12): 942-944.

• 综述 • 上一篇    下一篇

T淋巴母细胞淋巴瘤的研究进展

刘小兰, 苏丽萍   

  1. 030013 太原，山西医科大学附属山西省肿瘤医院血液科
  • 出版日期:2012-12-08 发布日期:2012-11-15
  • 通讯作者: 苏丽萍，E-mail:sulp2005@sohu.com E-mail:sulp2005@sohu.com

Research progress in T-cell lymphoblastic lymphoma

LIU  Xiao-Lan, SU  Li-Ping   

  1. Department of Hematology, Affiliated Shanxi Tumor Hospital, Shanxi Medical University, Taiyuan 030013, China
  • Online:2012-12-08 Published:2012-11-15
  • Contact: Corresponding author: SU Li-ping,E-mail:sulp2005@sohu.com E-mail:sulp2005@sohu.com

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2001

被引次数

7

摘要： T淋巴母细胞淋巴瘤（T-LBL）是非霍奇金淋巴瘤（NHL）中的一种少见类型，好发于儿童和青年，生物学特征类似于T细胞急性淋巴细胞白血病。T-LBL病变进展较快，传统NHL样化疗方案的疗效并不理想，目前已明确应采用急性淋巴细胞白血病样方案治疗，造血干细胞移植（HSCT）可能改善LBL患者特别是难治复发患者的生存。

关键词: 淋巴瘤, T细胞, 预后, 治疗

Abstract: T-lymphoblastic lymphoma (T-LBL) is a rare form of non-Hodgkin lymphoma (NHL), which is biologically similar to T-acute lymphoblastic leukemia(ALL),and occurs most frequently in childhood and adolescence. T-LBL progresses fast.The treatment of LBL with conventional chemotherapy regimens for NHL has shown relatively low rates of complete remission  and of disease-free survival. Now,it is reasonable to treat patients with LBL with the current ALL-type protocols, and hematopoietic stem cell transplantation may yield a more favorable overall survival (OS) in T-LBL patients, especial in relapsed or refractory LBL patients.

Key words: Lymphoma,T cell, Prognosis, Therapy