国际肿瘤学杂志 ›› 2012, Vol. 39 ›› Issue (12): 939-941.

• 综述 • 上一篇    下一篇

宫颈小细胞癌研究进展

张英丽, 陈雅卿, 郑爱文   

  1. 310022 浙江省肿瘤医院妇科
  • 出版日期:2012-12-08 发布日期:2012-11-15
  • 通讯作者: 张英丽,E-mail:pandazhang@163.com E-mail:pandazhang@163.com

Advances in study of cervical small cell carcinoma

ZHANG  Ying-Li, CHEN  Ya-Qing, ZHENG  Ai-Wen   

  1. Department of Gynecology, Zhejiang Cancer Hospital, Hangzhou 310022, China
  • Online:2012-12-08 Published:2012-11-15
  • Contact: Corresponding author:ZHANG Ying-li, E-mail: pandazhang@163.com E-mail:pandazhang@163.com

摘要: 宫颈小细胞癌属神经内分泌癌,是一种少见的高度恶性妇科肿瘤,侵袭性强,易早期转移,复发率高,预后差。其诊断主要依靠组织病理形态学,免疫组织化学标记物有助于诊断。治疗以手术辅以化疗、放疗综合治疗为主,术后化疗采用EP方案(铂类+依托泊甙)、VAC方案(长春新碱+表柔比星+环磷酰胺)或TP方案(紫杉醇+卡铂)可明显改善患者预后。

关键词: 宫颈肿瘤, 外科手术, 药物疗法, 放射疗法

Abstract: Small cell carcinoma of cervix (SCCC) is a rare and high malignant neuroendocrine tumor. Because of its strong invasion, metastasis in early stage and easy recurrence, the prognosis is poor. Its diagnosis is based on pathomorphology, and immune-histochemistry biomarkers can improve its diagnosis. Combined therapy is recommended. Postoperative platinum/etoposide(PE), vincristine/adriamycin/cyclophosphamide(VAC) or taxel /carboplatin(TP) chemotherapy can improve the prognosis.

Key words: Uterine cervical neoplasms, Surgical procedures, operative, Drug therapy, Radiotherapy