国际肿瘤学杂志

国际肿瘤学杂志 ›› 2014, Vol. 41 ›› Issue (4): 286-289.doi: 10.3760/cma.j.issn.1673422X.2014.04.015

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肺结核与肺癌相关性的临床研究

张琳琳, 郭其森   

  1. 250117 济南，山东省肿瘤医院内科；济南大学山东省医学科学院医学与生命科学学院（张琳琳、郭其森）；山东省胸科医院呼吸内科（张琳琳）
  • 出版日期:2014-04-08 发布日期:2014-03-17
  • 通讯作者: 郭其森 E-mail:guoqs369@163.com

Clinical study on the relationship between pulmonary tuberculosis and lung cancer

 ZHANG  Lin-Lin, GUO  Qi-Sen   

  1. Department of Internal Medicine, Shandong Tumor Hospital; School of Medicine and Life Science, University of Ji′nanShandong Academy of Medicine Sciences; Department of Respiratory, Shandong Chest Hospital, Ji′nan 250117, China
  • Online:2014-04-08 Published:2014-03-17
  • Contact: Guo Qisen E-mail:guoqs369@163.com

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1446

被引次数

3

摘要： 肺结核发生发展主要是炎症介质反应的结果，而肺癌致病机制复杂，涉及多基因多分子的参与。肺结核患者的免疫异常、抗结核药物、瘢痕修复、慢性炎症刺激以及结核菌素的毒力均与肺癌的发生密切相关。肺结核合并肺癌患者的治疗包括联合化疗、手术以及放疗等有限手段。

关键词: 肺肿瘤, 结核, 肺, 癌基因, 基因, 肿瘤抑制

Abstract: The pathogenesis of pulmonary tuberculosis involves inflammatory mediators reaction, and the pathogenesis of lung cancer is complex, involving multiple genes and molecules. The lung cancer has some relevance with pulmonary tuberculosis in terms of immune abnormalities, antituberculosis drugs, scar repair, chronic inflammation and tuberculin virulence. The treatment of tuberculosis patients with lung cancer is limited to chemotherapy, surgery and radiotherapy.

Key words: Lung neoplasms, Tuberculosis, pulmonary, Oncogenes, Genes, tumor suppressor