国际肿瘤学杂志

国际肿瘤学杂志 ›› 2014, Vol. 41 ›› Issue (4): 283-285.doi: 10.3760/cma.j.issn.1673422X.2014.04.014

• 综述 • 上一篇    下一篇

晚期非小细胞肺癌的维持治疗

吕昆象, 李文辉, 侯宇, 张明, 王丽, 奚江   

  1. 650118 云南省肿瘤医院昆明医科大学第三附属医院放疗科
  • 出版日期:2014-04-08 发布日期:2014-03-17
  • 通讯作者: 李文辉 E-mail:wenhuili64@aliyun.com

Maintenance treatment of advanced nonsmall cell lung cancer

Lyu Kun-Xiang , LI  Wen-Hui, HOU  Yu, ZHANG  Ming, WANG  Li, XI  Jiang   

  1. Department of Radiation Oncology, Third Affiliated Hospital of Kunming Medical University, Yunnan Tumor Hospital, Kunming 650118, China
  • Online:2014-04-08 Published:2014-03-17
  • Contact: Li Wenhui E-mail:wenhuili64@aliyun.com

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摘要： 目前晚期非小细胞肺癌（NSCLC）一线治疗标准是以铂类为基础的双药化疗。标准疗程化疗后当疾病处于控制状态时下一步处理存在着很大争议，维持治疗逐渐应用于晚期NSCLC的治疗中。晚期NSCLC维持治疗可分为继续维持治疗与换药维持治疗，目前多用于维持治疗的培美曲塞和厄洛替尼已被证实可提高总体生存率。

关键词: 癌, 非小细胞肺, 维持治疗, 靶向治疗

Abstract: Currently platinumbased double chemotherapy is the standard firstline treatment for advanced nonsmall cell lung cancer (NSCLC). When the disease is under control, the next step after a standard course of chemotherapy is controversial, and maintenance treatment is used in the treatment of advanced NSCLC increasingly. Maintenance treatment of advanced NSCLC includes continue maintenance treatment and  medication changed maintenance therapy. currently used for maintenance therapy with pemetrexed and erlotinib are shown to improve overall survival, which are usually used for maintenance treatment.

Key words: Carcinoma, nonsmallcell lung, Maintenance treatment, Targeted therapy