国际肿瘤学杂志

国际肿瘤学杂志 ›› 2018, Vol. 45 ›› Issue (11): 685-687.doi: 10.3760/cma.j.issn.1673-422X.2018.11.010

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大气压低温等离子体抗肿瘤作用机制及其应用

邬岚，李巍，张大伟，姜学钧   

  1. 110001 沈阳，中国医科大学附属第一医院耳鼻咽喉科（邬岚、李巍、姜学钧）；沈阳理工大学自动化与电气工程学院 （张大伟）
  • 出版日期:2018-11-08 发布日期:2018-12-21
  • 通讯作者: 姜学钧，Email: djiangxj@163.com E-mail:djiangxj@163.com
  • 基金资助:
    沈阳市科技计划（18-014-4-14）

Anti-tumor mechanism and application of tumor treatment of cold atmosphere plasma

Wu Lan, Li Wei, Zhang Dawei, Jiang Xuejun   

  1. Department of Otorhinolaryngology, First Affiliated Hospital of China Medical University, Shenyang 110001, China
  • Online:2018-11-08 Published:2018-12-21
  • Contact: Jiang Xuejun, Email: djiangxj@163.com E-mail:djiangxj@163.com
  • Supported by:
    Science and Technology Project of Shenyang of China (18-014-4-14)

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摘要： 大气压低温等离子体（CAP）是由气体热不平衡电离所产生的第四态物质，其可通过调节一系列相关基因及细胞信号通路实现对肿瘤生物学行为的影响。CAP具有放化疗增敏效应，并且与选择性抗肿瘤的特性密切相关，未来可能成为一种非常有效的新型肿瘤治疗方式。

关键词: 肿瘤, 活性氧, DNA, 大气压低温等离子体

Abstract: Cold atmosphere plasma (CAP) is the fourth state substance produced by gas thermal unbalanced ionization, which can influence tumor biological behavior by regulating a series of related genes and cell signaling pathways. CAP has the chemotherapeutic sensitization and is closely related to the characteristic of selective anti-tumor effect, which may become a very effective new treatment in the future

Key words: Neoplasms, Reactive oxygen species, DNA, Cold atmosphere plasma