乳腺癌保乳术后大分割放疗的研究进展

doi:10.3760/cma.j.issn.1673-422X.2018.09.013

国际肿瘤学杂志 ›› 2018, Vol. 45 ›› Issue (8): 570-573.doi: 10.3760/cma.j.issn.1673-422X.2018.09.013

乳腺癌保乳术后大分割放疗的研究进展

郑林晶，董银萍，胡兵，夏重升，李宝生，黄伟

250200 济南大学山东省医学科学院医学与生命科学学院（郑林晶、董银萍、胡兵）；济宁医学院附属医院肿瘤科（郑林晶、夏重升）；山东大学附属山东省肿瘤医院放疗六病区（李宝生、黄伟）

出版日期:2018-09-08 发布日期:2018-11-15
通讯作者: 黄伟 E-mail:alvinbird@163.com
基金资助:
国家自然科学基金（81773232、81530060）；山东省自然科学基金（ZR2015QZ09）；泰山学者建设工程（ts20120505）

Research progress of hypofractionated whole breast irradiation after breast conserving surgery

Zheng Linjing, Dong Yinping, Hu Bing, Xia Chongsheng, Li Baosheng, Huang Wei

School of Medicine and Life Sciences, University of Ji′nan Shandong Academy of Medical Sciences, Ji′nan 250200, China; Department of Oncology, Affiliated Hospital of Jining Medical University, Jining 272000, China

Online:2018-09-08 Published:2018-11-15
Contact: Huang Wei E-mail:alvinbird@163.com
Supported by:
National Natural Science Foundation of China (81773232, 81530060); Natural Science Foundation of Shandong Province of China (ZR2015QZ09); Taishan Scholar Construction Project (ts20120505)

摘要/Abstract

摘要： 乳腺癌保乳术联合大分割放疗已成为早期乳腺癌治疗的新模式。临床研究表明乳腺癌的α/β值比一般肿瘤低，更适合大分割放疗。大分割放疗具有良好的经济效益，多项经典随机对照研究长期随访结果表明，全乳腺大分割放疗是有效和安全的。随着大分割放疗的广泛应用，这项技术也逐渐被拓展到区域淋巴结照射、乳房切除术后放疗以及乳腺导管原位癌的放疗中。

关键词: 乳腺肿瘤, 放射疗法, 治疗效果, 保乳术, 不良反应

Abstract: Hypofractionated radiotherapy after breast conserving surgery has become a new standard treatment of early breast cancer. Clinical researches show that α/β value of breast cancer is lower than that of other tumors, and the breast cancer is more suitable for hypofractionated radiotherapy. Hypofractionated radiotherapy has good economic benefits, and longterm followup results from a number of classical randomized controlled studies have shown that hypofractionated whole breast irradiation is effective and safe. With the extensive application of hypofractionated irradiation, this technology has been gradually extended to regional nodal irradiation, postmastectomy radiotherapy and breast ductal carcinoma in situ.

Key words: Breast neoplasms, Radiotherapy, Treatment effect, Breast conserving surgery, Sideeffects

郑林晶，董银萍，胡兵，夏重升，李宝生，黄伟. 乳腺癌保乳术后大分割放疗的研究进展[J]. 国际肿瘤学杂志, 2018, 45(8): 570-573.

Zheng Linjing, Dong Yinping, Hu Bing, Xia Chongsheng, Li Baosheng, Huang Wei. Research progress of hypofractionated whole breast irradiation after breast conserving surgery[J]. Journal of International Oncology, 2018, 45(8): 570-573.

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乳腺癌保乳术后大分割放疗的研究进展

Research progress of hypofractionated whole breast irradiation after breast conserving surgery

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