恶性胸膜间皮瘤靶向治疗进展

doi:10.3760/cma.j.issn.1673-422X.2014.01.017

摘要/Abstract

摘要： 恶性胸膜间皮瘤（MPM）是胸膜罕见的恶性肿瘤，由于其潜伏期约为20年，目前正是该疾病的高发阶段。由于该疾病发现时大部分已处于晚期，除了经典的培美曲塞联合顺铂一线化疗方案疗效确定之外，手术、放疗及二三线化疗疗效仍未知。近年来发展迅猛的分子靶向治疗又为MPM的个体化治疗提供了新的方向。

关键词: 基因, 肿瘤, 恶性胸膜间皮瘤, 分子靶向治疗

Abstract: Malignant pleural mesothelioma (MPM) is a rare form of cancer with latency period of 20 years, and it is now a period of high flows of MPM. It is often detected in late stages, and the efficacy of surgery, radiotherapy and second/thirdline chemotherapy still remains unknown except the classical firstline chemotherapy regimen contains pemetrexed and cisplatin. With the development of molecular targeted therapy, a new direction for individual therapy of MPM patient has been provided for the past few years.

Key words: Genes, Neoplasms, Malignant pleural mesothelioma, Molecular targeted therapy

程蕾, 许亚萍, 毛伟敏. 恶性胸膜间皮瘤靶向治疗进展[J]. 国际肿瘤学杂志, 2014, 41(1): 52-55.

Cheng Lei, Xu Yaping, Mao Weimin. Molecular targeted therapy of malignant pleural mesothelioma[J]. Journal of International Oncology, 2014, 41(1): 52-55.

参考文献

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