国际肿瘤学杂志 ›› 2024, Vol. 51 ›› Issue (11): 723-727.doi: 10.3760/cma.j.cn371439-20240618-00122

• 综述 • 上一篇    下一篇

超声靶向微泡破坏技术在肝癌治疗中的应用研究进展

蒋琼, 余进洪()   

  1. 川北医学院附属医院超声科,南充 637000
  • 收稿日期:2024-06-18 修回日期:2024-07-03 出版日期:2024-11-08 发布日期:2024-12-26
  • 通讯作者: 余进洪 E-mail:yujinhong@nsmc.edu.cn
  • 基金资助:
    南充市2022年市校科技战略合作专项基金(22SXQT0302)

Research progress on the application of ultrasound-targeted microbubble destruction technology in the treatment of liver cancer

Jiang Qiong, Yu Jinhong()   

  1. Department of Ultrasound, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, China
  • Received:2024-06-18 Revised:2024-07-03 Online:2024-11-08 Published:2024-12-26
  • Contact: Yu Jinhong E-mail:yujinhong@nsmc.edu.cn
  • Supported by:
    Nanchong 2022 Municipal School Science and Technology Strategic Cooperation Special Fund(22SXQT0302)

摘要:

肝癌常用的治疗方法有消融治疗、手术切除、肝移植等,随着超声治疗技术及分子影像技术的进一步发展,超声靶向微泡破坏(UTMD)技术成为了一种新兴肿瘤诊治手段,超声微泡不仅能诊断显影,而且还可作为一种新型的药物或基因的传递系统,实现通过靶向传递药物或基因来治疗疾病。在肝癌的治疗研究中,该技术具有巨大潜力,探讨UTMD在肝癌治疗中的机制、应用以及相关问题,可为肝癌患者带来新的治疗选择。

关键词: 肝肿瘤, 微泡, 超声透入疗法

Abstract:

Commonly used treatments for liver cancer include ablation therapy, surgical resection, liver transplantation, etc. With the further development of ultrasound therapy technology and molecular imaging technology, ultrasound-targeted microbubble destruction (UTMD) technology has become an emerging means of tumor diagnosis and treatment. Ultrasound microbubbles can not only diagnose and develop, but also can be used as a new drug or gene delivery system, enabling targeted delivery of drugs or genes to treat diseases. This technology has great potential in the treatment of liver cancer. Exploring the mechanism, application and related issues of UTMD in the treatment of liver cancer can bring new treatment options for liver cancer patients.

Key words: Liver neoplasms, Microbubbles, Phonophoresis