The expression and role of monocarboxylate transporter 1 in tumor

doi:10.3760/cma.j.issn.1673422X.2015.11.010

Journal of International Oncology ›› 2015, Vol. 42 ›› Issue (11): 835-837.doi: 10.3760/cma.j.issn.1673422X.2015.11.010

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The expression and role of monocarboxylate transporter 1 in tumor

Tai Shanshan, Wang Juan, Cheng Bin.

Department of Oral Medicine, Guanghua School of Stomatology, Sun Yatsen University, Guangdong Provincial Key Laboratory of Stomatology, Guangzhou 510055, China

Online:2015-11-08 Published:2015-09-30
Contact: Cheng Bin E-mail:chengbin@mail.sysu.edu.cn

Abstract

Abstract: The monocarboxylate transporters (MCTs) family, especially MCT1, plays an important role in tumor metabolism. MCT1 mediates a variety of monocarboxylic acids across the plasma membrane, and determines to take in or export lactic acid according to the metabolic state, thus maintaining the special tumor cells metabolism model. Considering the emerging evidence for the role of MCT1 in the tumor genesis, metabolism, invasion and metastasis, MCT1 is expected to be a new target for cancer therapy. 【Key words】Neoplasms; Metabolism; Monocarboxylate transporter 1

Key words: Neoplasms, Metabolism, Monocarboxylate transporter 1

Tai-Shan-Shan, WANG Juan, CHENG Bin. The expression and role of monocarboxylate transporter 1 in tumor[J]. Journal of International Oncology, 2015, 42(11): 835-837.

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The expression and role of monocarboxylate transporter 1 in tumor

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