Journal of International Oncology ›› 2014, Vol. 41 ›› Issue (6): 422-424.

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Progress of lentiviral vector on neoplasms gene therapy research

 NIU  Xin, DENG  Zhi-Hua   

  1. Department of Gastroenterology, Second Hospital of Shanxi Medical University, Taiyuan 030001, China
  • Online:2014-06-08 Published:2014-05-08
  • Contact: Deng Zhihua E-mail:ykdzh@hotmail.com

Abstract: Lentiviral vectors (LV), a special member of retroviral vectors, has become hot in gene therapy research. Studies have shown that LV can make exogenous gene expressed stably in tumor cells. As a tool for transportation, LV plays a significant role in the gene therapy of digestive system, hematologic system and gynecological tumor, which provides a promising new way for neoplasms gene therapy.

Key words: Lentivirus, Neoplasms, Genetic therapy