Abstract: Cancerrelated fatigue(CRF) is one of the important symptoms for cancer patients, especially for the long-term survival patients after treatment. Its complexity and interdependency with other symptoms make it difficult to identify the clear underlying mechanisms. No single etiologic model provides a satisfactory explanation of cancer-related fatigue. For mild fatigue, non-pharmacological therapy is recommended. Non-pharmacological therapy combined with pharmacological therapies is recommended for patients with moderate and severe fatigue.

Key words: Neoplasms, Fatigue, Quality of life