Journal of International Oncology ›› 2026, Vol. 53 ›› Issue (7): 388-397.doi: 10.3760/cma.j.cn371439-20260308-00054

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Chinese expert consensus on the correlation between intestinal microecology and hematopoietic stem cell transplantation (2026 Edition)

Tumor and Microecology Committee of the Chinese Anti-Cancer Association   

  • Received:2026-03-08 Online:2026-07-08 Published:2026-06-25
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    Practice guideline registration: International Practice Guideline Registry Platform (PREPARE-2026CN1066)

Abstract:

Hematopoietic stem cell transplantation (HSCT) affects intestinal flora homeostasis, and intestinal microecology may also affect the prognosis of HSCT patients through multiple mechanisms. To gain a deeper understanding of intestinal microecology and HSCT to address the key issues of correlation, and to learn and absorb the latest research progress, the Tumor and Microecology Committee of the Chinese Anti-Cancer Association organized relevant experts to revise on the basis of the "Chinese expert consensus on the correlation between intestinal microecology and hematopoietic stem cell transplantation " (2021 Edition) and proposed the "Chinese expert consensus on the correlation between intestinal microecology and hematopoietic stem cell transplantation (2026 Edition)". This consensus, based on the latest domestic and international literature and combined with the latest technology and research in the discipline, presents 9 recommendations regarding issues such as the indications of intestinal microecology in hematopoietic stem cell transplantation, for clinicians to refer to in practice. This consensus can not only provide practical guidance for clinicians, but also lay a foundation for further in-depth research in the fields of oncology and microecology.

Key words: Gastrointestinal microbiome, Hematopoietic stem cell transplantation, Consensus, Correlation