Research progress of HOXC10 in digestive system neoplasms

doi:10.3760/cma.j.cn371439-20250704-00134

Abstract

Abstract:

HOXC10 is a homeobox gene that is closely related to the occurrence and development of digestive system neoplasms. In esophageal cancer， gastric cancer， liver cancer and colorectal cancer， the expression of HOXC10 shows varying degrees of increase， which is closely related to the biological processes such as tumor cell proliferation， metastasis and invasion， apoptosis， and drug resistance， and it participates in tumor regulation through various pathways， which exerts a carcinogenic effect and affects the prognosis of patients. HOXC10 is expected to be a potential molecular target for digestive system neoplasms.

Key words: Digestive system neoplasms, Gene expression, Carcinogenesis, HOXC10

Song Xueqin, Li Mingying. Research progress of HOXC10 in digestive system neoplasms[J]. Journal of International Oncology, 2025, 52(12): 787-790.

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