Journal of International Oncology ›› 2025, Vol. 52 ›› Issue (1): 43-47.doi: 10.3760/cma.j.cn371439-20240528-00006

• Review • Previous Articles     Next Articles

Research progress in treatment strategies and prognostic factors for stage pT2-3N0M0 thoracic esophageal squamous cell carcinoma

Yu Yang1, Tang Shimin2, Yang Lu2, Li Na2()   

  1. 1Department of Clinical Medicine, North Sichuan Medical College, Nanchong 637000, China
    2Department of Cancer Center, Suining Central Hospital of Sichuan Province, Suining 629000, China
  • Received:2024-05-28 Revised:2024-11-26 Online:2025-01-08 Published:2025-01-21
  • Contact: Li Na E-mail:lny.yl@163.com
  • Supported by:
    Sichuan Key R&D Program(2023YFS0488);Research Topic of Suining Central Hospital(2022ypj03)

Abstract:

Although patients with stage pT2-3N0M0 thoracic esophageal squamous cell carcinoma are staged earlier, their postoperative local recurrence and distant metastasis rates are higher, resulting in a low five-year survival rate of such patients. The current neoadjuvant treatment for such patients is still in the research stage, and whether to give adjuvant radiotherapy and chemotherapy after surgery is still controversial. In addition, the prognostic factors of patients with pT2-3N0M0 thoracic esophageal squamous cell carcinoma have not yet been clarified, and the causes of recurrence and metastasis are not yet clear. Therefore, it is of great significance to clarify treatment strategies and explore the impact of prognostic factors on improving the survival rate of such patients, which is expected to provide new directions for improving the prognosis and survival rate of patients with pT2-3N0M0 thoracic esophageal squamous cell carcinoma.

Key words: Esophageal squamous cell carcinoma, Antineoplastic protocols, Prognosis