Advances in the study of EVI1 in acute myeloid leukemia

doi:10.3760/cma.j.cn371439-20231218-00078

Abstract

Abstract:

Acute myeloid leukemia （AML） is a common malignant disease of the hematological system， with high EVI1 expression accounting for 8%-10% of adult AML. Studies have shown that high EVI1 expression plays an important role in the treatment and prognosis of AML. In recent years， researchers have continuously revealed the structure and role of EVI1， but its mechanism of mediating AML has not been fully clarified. Therefore， systematically exploring the role of EVI1 in AML may provide a useful reference for the precise treatment of AML patients with high EVI1 expression.

Key words: Myeloid ecotropic viral integration site 1 protein, Leukemia, myeloid, acute, Gene expression, Therapy

Wu Shiwei, Pei Kangjia, Zhang Dongxing, Qin Zhanyu, Guo Shuxia. Advances in the study of EVI1 in acute myeloid leukemia[J]. Journal of International Oncology, 2024, 51(7): 474-477.

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