Enrichment methods and clinical application of circulating tumor cells

doi:10.3760/cma.j.cn371439-20200629-00033

Abstract

Abstract:

As an emerging tumor marker, the rarity and heterogeneity of circulating tumor cells (CTCs) increase the difficulty of detection. In recent years, CTCs enrichment technology based on biophysical, biochemical and microfluidic properties has been continuously developed, which has promoted the research and application of CTCs in malignant tumors diagnosis, clinical treatment and prognosis evaluation. Although there are still some deficiencies in the detection of CTCs, with the interdisciplinary integration, CTCs will play increasingly important roles in the diagnosis and treatment of malignant tumors.

Key words: Neoplastic cells, circulating, Biomarkers, Cytological techniques, Diagnosis

Ning Dawei, Ou Yang, Cui Kai, Li Sheng, Gao Dehai. Enrichment methods and clinical application of circulating tumor cells[J]. Journal of International Oncology, 2021, 48(3): 167-171.

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