Journal of International Oncology ›› 2018, Vol. 45 ›› Issue (7): 440-443.doi: 10.3760/cma.j.issn.1673-422X.2018.07.012

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Application of methylation detection of SEPT9 gene in early diagnosis of colorectal cancer

Dai Chunyang, Li Ming   

  1. Department of Clinical Laboratory, Western Branch of Anhui Provincial Hospital, Hefei 230031, China
  • Online:2018-07-08 Published:2018-07-31
  • Contact: Li Ming, Email: liming19831002@163.com E-mail:liming19831002@163.com
  • Supported by:

    Natural Science Foundation of Anhui Province of China (1308085QH144)

Abstract: SEPT9 gene belongs to a member of SEPT gene family. In recent years, it has been found that SEPT9 gene is highly methylated in colorectal cancer cells. Detecting SEPT9 gene methylation in the development of colorectal cancer, the application of different specimen types for the detection of SEPT9 gene methylation and the development of SEPT9 gene methylation detection methods can provide evidence for early diagnosis of colorectal cancer.

Key words: Colorectal neoplasms, Methylation, SEPT9 gene