Journal of International Oncology ›› 2017, Vol. 44 ›› Issue (5): 366-368.doi: 10.3760/cma.j.issn.1673422X.2017.05.010

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Research progress of the patrolling monocytes in tumor

Fang Ping, Xu Ke, Chen Bin, Gao Hong, Zhu Yanwei   

  1. Department of Oncology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China
  • Online:2017-05-08 Published:2017-04-19
  • Contact: Zhu Yanwei E-mail:zhuyanwei@csco.org.cn
  • Supported by:

    National Natural Science Foundation of China (81503434)

Abstract: Patrolling monocyte (PMo) is a subset of monocytes. Its main function is patrolling vascular endothelium and removing cellular debris from the microvasculature. Studies have revealed that PMo can inhibit the growth of tumor cells, recruiting NK cells to kill tumor cells. PMo can prevent tumor cells metastasis to the lung, which plays a role of immunosurveillance. PMo may be a target for cancer immunotherapy.

Key words: Neoplasms, Immune, Monocytes