Journal of International Oncology ›› 2015, Vol. 42 ›› Issue (5): 355-357.doi: 10.3760/cma.j.issn.1673422X.2015.05.009

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Clinical relativity of PDCD5 with tumor

  

  1. Clinical Medicine Science, School of Basic Medicine
  • Online:2015-05-08 Published:2015-05-12
  • Contact: Liu Wei pkulw@aliyun.com

Abstract: Programmed cell death 5 (PDCD5) is a new kind of programmed cell death regulation and control gene. PDCD5's expression is widespread, and evolution is conservative. PDCD5 has the effect of promoting a wide variety of tumor cells to apoptosis and inhibiting proliferation, such as lung cancer, liver cancer et al. Several laboratories' discoveries show that PDCD5's expression is significantly decreased when in some disease cases, especially in tumor cases. PDCD5, which is related to the clinical relevance of the tumor, has a great clinical value of discovering, diagnosis and treatment of the tumor.