Abstract: The BRAF^V600E mutation in papillary thyroid carcinoma is the most common genetic event, which is an invasive tumor clinical phenotype and a poor prognosis indicator. The BRAF^V600E mutation detection has an important guiding significance for the differential diagnosis of malignant thyroid nodules on preoperative, guiding the surgical resection range of thyroid cancer, judging the patient’s prognosis and guiding the subsequent  treatment of postoperative

Key words: color: black, font-family: "Times New Roman", mso-ansi-language: EN-US, mso-fareast-language: ZH-CN, mso-bidi-language: AR-SA, mso-fareast-font-family: 宋体, mso-font-kerning: 1.0pt">Thyroid neoplasms, Adenocarcinoma, papillary, Point mutation