Research progress on the signaling pathways regulated by microRNAs in cancer cachexia muscle atrophy

doi:10.3760/cma.j.cn371439-20241108-00108

Abstract

Abstract:

Cancer cachexia is a complex multifactorial disease that can lead to significant reduction of skeletal muscle mass. MicroRNAs （miRNAs） are non-coding RNAs that are closely related to the development of cancer cachexia muscle atrophy. Studies have shown that miRNAs play an important role in the occurrence and development of cancer cachexia muscle atrophy by regulating various signaling pathways， but the mechanism by which miRNAs mediate cancer cachexia muscle atrophy has not been fully clarified. A systematic investigation of the role of miRNAs in cancer cachexia muscle atrophy may provide useful references for the precise treatment of patients with cancer cachexia muscle atrophy.

Key words: MicroRNAs, Neoplasms, Cachexia, Muscle atrophy, Signal transduction

Fan Yuyu, Jia Junmei. Research progress on the signaling pathways regulated by microRNAs in cancer cachexia muscle atrophy[J]. Journal of International Oncology, 2025, 52(10): 633-636.

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