Metric evaluation of quality of life instruments for cancer patients-brain neoplasm (QLICP-BN)

doi:10.3760/cma.j.cn371439-20201019-00029

Abstract

Abstract:

Objective To understand the reliability and validity of quality of life instruments for cancer patients-brain neoplasm [QLICP-BN (V1.0)], a self-developed quality of life scale for cancer patients. Methods The quality of life of 112 patients with brain neoplasms in Yunnan Cancer Hospital from March 2012 to November 2013 was measured. The general data questionnaire and QLICP-BN (V1.0) were used for data collection. The reliability, validity and responsiveness of the scale were tested, and then the metric characteristics of the scale were evaluated. Results The split-half reliability of the total score of the scale was 0.95, the Cronbach α coefficient was 0.92, and the test-retest correlation coefficient r was 0.78. After extracting common factors by the principal component method and rotating with the maximum variance, the specific module obtained three principal components, and the cumulative variance contribution rate was 64.18%. The score of specific module was 75.30±17.44 before treatment and 78.91±12.20 after treatment (t=-2.481, P=0.015). The total score of scale before treatment was 65.26±12.29, and that after treatment was 69.62±10.41, with a statistically significant difference (t=-4.492, P<0.001). The total responsiveness of the scale was 0.456, showing moderate responsiveness. Conclusion QLICP-BN (V1.0) has good reliability, validity and a certain degree of responsiveness. It can be used as a measurement tool for the quality of life of patients with brain neoplasms in China.

Key words: Brain neoplasms, Quality of life, Reproducibility of results

Han Xiaoyu, He Jun, Wan Chonghua, Luo Jiahong, Bai Gang, Zhang Jianghui, Meng Qiong. Metric evaluation of quality of life instruments for cancer patients-brain neoplasm (QLICP-BN)[J]. Journal of International Oncology, 2021, 48(3): 143-149.

Figures/Tables 6

领域代码	领域平均得分( $x -$ ±s)		t值	P值	重测r	ICC	95%CI
领域代码	T1	T2	t值	P值	重测r	ICC	95%CI
PHD	51.71±17.28	51.64±16.41	0.061	0.952	0.880	0.878	0.795~0.929
PSD	63.71±15.86	64.50±14.29	-0.600	0.551	0.814	0.809	0.686~0.887
SOD	52.00±16.24	52.42±16.54	-0.244	0.808	0.728	0.728	0.566~0.836
SSD	78.75±16.26	79.92±16.36	-1.147	0.257	0.903	0.903	0.835~0.944
SPD	74.81±17.08	74.35±11.08	0.275	0.785	0.723	0.660	0.469~0.792
TOT	64.87±12.50	65.86±10.66	-0.896	0.375	0.784	0.774	0.634~0.865

条目	PHD	PSD	SOD	SSD		SPD
GPH1	0.521^a	0.312^a	0.318^a	0.450^a		0.378^a
GPH2	0.405^a	0.175	0.165	0.294^a		0.217^a
GPH3	0.390^a	0.524^a	0.213^a	0.330^a		0.341^a
GPH4	0.672^a	0.474^a	0.508^a	0.211^a		0.563^a
GPH5	0.679^a	0.304^a	0.300^a	0.019		0.253^a
GPH6	0.883^a	0.582^a	0.406^a	0.301^a		0.443^a
GPH7	0.858^a	0.509^a	0.371^a	0.294^a		0.459^a
GPS1	0.380^a	0.688^a	0.370^a	0.469^a		0.279^a
GPS2	0.372^a	0.748^a	0.367^a	0.460^a		0.344^a
GPS3	0.338^a	0.554^a	0.303^a	0.396^a		0.217^a
GPS4	0.571^a	0.631^a	0.468^a	0.379^a		0.408^a
GPS5	0.252^a	0.564^a	0.294^a	0.411^a		0.329^a
GPS6	0.582^a	0.620^a	0.444^a	0.179		0.445^a
GPS7	0.353^a	0.429^a	0.509^a	0.128		0.312^a
GPS8	0.348^a	0.697^a	0.479^a	0.296^a		0.328^a
GPS9	0.553^a	0.566^a	0.426^a	0.197^a		0.427^a
GPS10	0.352^a	0.443^a	0.323^a	0.220^a		0.415^a
GPS11	0.374^a	0.733^a	0.424^a	0.364^a		0.336^a
GPS12	0.228^a	0.245^a	0.040	-0.015		0.135
GSO1	0.212^a	0.360^a	0.516^a	0.026		0.171
GSO2	0.211^a	0.251^a	0.536^a	-0.145		0.185
GSO3	0.609^a	0.479^a	0.714^a	0.154		0.359^a
GSO4	0.284^a	0.214^a	0.587^a	0.169		0.235^a
GSO5	0.245^a	0.381^a	0.593^a	0.272^a		0.269^a
GSO6	0.277^a	0.489^a	0.601^a	0.298^a		0.204^a
GSS1	0.303^a	0.316^a	0.335^a	0.767^a		0.344^a
GSS2	0.209^a	0.269^a	0.040	0.583^a		0.133
GSS3	0.230^a	0.302^a	0.162	0.505^a		0.190^a
GSS4	0.192^a	0.255^a	0.111	0.785^a		0.365^a
GSS5	0.494^a	0.494^a	0.224^a	0.753^a		0.408^a
GSS6	0.347^a	0.403^a	0.232^a	0.590^a		0.184
GSS7	0.325^a	0.457^a	0.271^a	0.581^a		0.360^a
SBN1	0.064	0.098	0.148	0.365^a		0.382^a
SBN2	0.042	0.246^a	0.092	0.174		0.338^a
SBN3	0.307^a	0.394^a	0.214^a	0.467^a		0.649^a
SBN4	0.229^a	0.395^a	0.223^a	0.277^a		0.520^a
SBN5	0.359^a	0.279^a	0.222^a	0.186		0.614^a
SBN6	0.633^a	0.450^a	0.438^a	0.207^a		0.755^a
SBN7	0.604^a	0.501^a	0.494^a	0.177		0.674^a
SBN8	0.084	0.212^a	0.069	0.195^a		0.523^a
条目	PHD	PSD	SOD	SSD	SPD
SBN9	0.522^a	0.453^a	0.478^a	0.149	0.671^a
SBN10	0.363^a	0.338^a	0.114	0.332^a	0.693^a
SBN11	0.387^a	0.353^a	0.144	0.270^a	0.608^a
SBN12	0.605^a	0.446^a	0.529^a	0.209^a	0.660^a
SBN13	0.536^a	0.501^a	0.184	0.365^a	0.599^a

条目代码	公因子1	公因子2	公因子3	公因子4	公因子5	公因子6	公因子7	公因子8
GPH1	0.357	0.078	0.625	0.163	0.169	-0.100	-0.084	0.148
GPH2	0.409	0.098	0.362	-0.203	0.266	-0.110	0.097	0.317
GPH3	0.159	0.397	0.047	0.281	0.011	0.087	0.363	-0.514
GPH4	0.518	0.125	0.221	0.179	0.284	0.217	-0.185	0.221
GPH5	0.844	0.042	-0.130	0.061	0.049	-0.037	-0.008	-0.060
GPH6	0.817	0.162	0.097	0.057	0.060	0.353	0.070	-0.004
GPH7	0.785	0.072	0.150	0.074	0.052	0.320	0.065	-0.011
GPS1	0.097	0.705	0.229	0.189	0.170	0.041	0.229	0.012
GPS2	0.060	0.870	0.139	0.156	0.063	0.145	0.126	0.000
GPS3	0.176	0.821	0.146	0.037	0.054	-0.170	0.080	0.095
GPS4	0.401	0.082	0.283	0.560	0.044	0.181	0.142	-0.118
GPS5	-0.050	0.554	0.240	0.446	-0.167	0.031	-0.175	0.014
GPS6	0.385	0.055	0.019	0.089	0.233	0.757	0.067	0.081
GPS7	0.207	0.161	0.091	0.012	0.858	0.012	-0.049	-0.066
GPS8	0.037	0.550	0.053	0.627	0.006	0.092	-0.020	-0.053
GPS9	0.436	0.057	0.073	0.084	0.200	0.666	-0.051	0.094
GPS10	0.275	0.166	0.321	0.361	0.176	-0.027	-0.359	-0.482
GPS11	0.084	0.620	0.093	0.528	0.051	0.119	0.228	-0.124
GPS12	0.117	-0.047	-0.092	-0.421	0.161	0.669	0.052	-0.130
GSO1	0.009	0.081	-0.002	-0.061	0.664	0.466	0.027	0.219
GSO2	0.107	-0.080	-0.116	0.005	0.874	0.218	-0.065	0.009
GSO3	0.567	0.048	0.007	0.190	0.470	0.240	0.028	0.238
GSO4	0.191	0.117	0.101	0.219	0.114	0.099	-0.004	0.708
GSO5	0.078	0.109	0.187	0.793	-0.007	-0.089	0.017	0.161
GSO6	0.101	0.319	0.094	0.726	0.065	-0.149	0.153	-0.004
GSS1	0.046	0.138	0.733	0.181	0.009	0.005	0.208	0.140
GSS2	-0.042	0.112	0.197	0.120	-0.116	-0.058	0.789	-0.063
GSS3	-0.053	0.143	0.541	0.048	0.164	-0.057	0.393	-0.052
GSS4	-0.147	0.064	0.838	0.144	-0.165	0.136	0.038	-0.034
GSS5	0.190	0.306	0.700	0.049	-0.042	0.014	0.249	-0.077
GSS6	0.122	0.232	0.275	0.024	0.000	0.153	0.668	0.069
GSS7	0.079	0.388	0.497	0.349	-0.164	-0.037	0.070	-0.269

领域	领域平均分( $x -$ ±s)			t值	P值	SRM
领域	T1	T3		t值	P值	SRM
PHD	52.06±17.95		56.11±16.92	-2.782	0.007	0.283
PSD	63.94±15.09		67.83±13.93	-3.260	0.002	0.331
SOD	53.91±15.76		51.98±14.42	1.418	0.159	0.144
SSD	78.78±16.76		86.76±13.13	-6.011	<0.001	0.613
SPD	75.30±17.44		78.91±12.20	-2.481	0.015	0.252
TOT	65.26±12.29		69.62±10.41	-4.492	<0.001	0.456

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项目	例数	构成比(%)
性别
男	63	56.3
女	49	43.7
民族
汉族	96	85.7
少数民族	16	14.3
文化程度
小学	44	39.3
初中	51	45.5
高中或中专	12	10.7
大专及以上	5	4.5
婚姻
已婚	100	89.3
离异	1	0.9
未婚	11	9.8

领域	条目数	克朗巴赫系数α	分半信度
PHD	7	0.788	0.832
PSD	12	0.806	0.840
SOD	6	0.631	0.827
SSD	7	0.821	0.853
SPD	13	0.849	0.871
TOT	45	0.921	0.948