Mechanisms of microrobot in cancer therapy

doi:10.3760/cma.j.cn371439-20191016-00090

Abstract

Abstract:

Microrobots (from several millimetres down to a few micrometres in all dimensions) are constructed of nanoscale or molecular components and include various types of magneto-aerotactic bacteria microrobots, nanomotors, biohybrid magnetite microrobots, DNA nanorobots, soft-bodied robots and soft matter. Microrobots may enable applications in cargo delivery, targeting cancer, cellular manipulation and killing cancer. Microrobots swarms exhibit a variety of intriguing collective behaviors, and will serve as a functional bio-microrobot system for cancer "subtle therapy".

Key words: Neoplasms, Molecular motor proteins, Therapy, Microrobots, Nanorobotics

Zhang Baihong, Yue Hongyun. Mechanisms of microrobot in cancer therapy[J]. Journal of International Oncology, 2020, 47(10): 624-626.

Figures/Tables 1

References 22

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种类	结构	动力	控制	功能
磁控细菌机器人	人造细菌鞭毛/趋磁细菌群	细菌鞭毛运动	磁场	输送药物^[6,7]、靶向肿瘤^[14]
纳米马达	金纳米棒共轭多孔硅纳米囊泡	静脉血流	近红外激光控	输送药物^[8]
	中孔氧化硅纳米	尿素酶	底物依赖	靶向肿瘤^[15]
	超支化聚酰胺	一氧化氮	光控	操控细胞^[18]
	萘酞菁	过氧化氢	光控	清除肿瘤^[20]
续生物激活螺旋机器人	螺旋藻包裹Fe₃O₄	化学能	磁场	靶向肿瘤^[11]
DNA纳米机器人	DNA适配体连接核仁素和凝血酶	DNA分子激动	内皮细胞	靶向肿瘤^[12]
软体机器人	软体	磁弹性	自控	操控细胞^[16]
液态金属纳米机器人	金属镓	类细菌自运动	超声场	清除肿瘤^[21]