国际肿瘤学杂志 ›› 2016, Vol. 43 ›› Issue (1): 60-63.doi: 10.3760/cma.j.issn.1673,422X.2016.01.017

• 综述 • 上一篇    下一篇

肝内胆管细胞癌的治疗进展

罗梦超,丁超峰,吴健,郑树森   

  1. 310003杭州,浙江大学医学院附属第一医院肝胆外科 卫生部多器官联合移植研究重点实验室 感染性疾病诊治协同创新中心
  • 收稿日期:2015-08-02 出版日期:2016-01-08 发布日期:2015-12-03
  • 通讯作者: 郑树森 E-mail:shusenzheng@zju.edu.cn
  • 基金资助:

    国家高技术研究发展计划(2012AA021002);国家卫生和计划生育委员会公益性行业科研专项(201302009);浙江省自然科学基金(LQ15H160002)

Treatment progress of intrahepatic cholangiocarcinoma

Luo Mengchao, Ding Chaofeng, Wu Jian, Zheng Shusen   

  1. Department of Hepatobiliary Surgery, First Affiliated Hospital, School of Medicine, Zhejiang University; Key Laboratory of Combined Multiorgan Transplantation, Ministry of Public Health; Collaborative Innovation Center of Diagnosis and Treatment of Infectious Diseases, Hangzhou 310003, China
  • Received:2015-08-02 Online:2016-01-08 Published:2015-12-03
  • Contact: Zheng Shusen E-mail:shusenzheng@zju.edu.cn
  • Supported by:

    National High Technology Research and Development Program of China (863 Program) (2012AA021002); Special Fund for Health Research in the Public Welfare of National Health and Family Planning Commission of China (201302009); Natural Science Foundation of Zhejiang Province of China (LQ15H160002)

摘要: 肝内胆管细胞癌(ICC)当前首选治疗手段仍为手术治疗。吉西他滨联合顺铂全身化疗方案可推荐为不可切除ICC患者的标准治疗方案。近年来新辅助治疗联合肝移植方案的提出为肝移植治疗ICC开拓了新的治疗前景。此外,放疗、介入治疗、射频消融治疗、分子靶向治疗等也是综合治疗ICC的重要组成部分。

关键词: 胆管, 肝内, 胆管肿瘤, 治疗学, 预后

Abstract: Surgical resection is still the mainstay for treatment of intrahepatic cholangiocarcinoma (ICC). Gemcitabine and cisplatin is a systemic therapy practice standard for patients with nonresectable ICC. Neoadjuvant therapy with liver transplantation may be a new therapeutic option for patients with ICC. In addition, radiotherapy, hepatic intraarterial therapy, ablation therapy and molecular targeted therapy are important components of comprehensive therapy for ICC.

Key words: Bile ducts, intrahepatic, Bile duct neoplasms, Therapeutics