国际肿瘤学杂志 ›› 2015, Vol. 42 ›› Issue (12): 916-919.doi: 10.3760/cma.j.issn.1673-422X.2015.12.009

• 综述 • 上一篇    下一篇

局部晚期乳腺癌新辅助化疗

刘慧,芮景   

  1. 241000 芜湖,皖南医学院附属弋矶山医院肿瘤内科
  • 出版日期:2015-12-08 发布日期:2015-11-10
  • 通讯作者: 芮景 E-mail:ruijing1956@sina.com

Neoadjuvant chemotherapy for locally advanced cancer

Liu Hui, Rui Jing   

  1. Department of Oncology, Yijishan Hospital Affiliated to Wannan Medical College, Wuhu 241000, China
  • Online:2015-12-08 Published:2015-11-10
  • Contact: Rui Jing E-mail:ruijing1956@sina.com

摘要: 新辅助化疗是局部晚期乳腺癌综合治疗的常用手段之一,以蒽环类和紫杉烷类为主要化疗药物。近年来,分子靶向药物在显著提高化疗疗效的同时,也为临床提供了更多选择和治疗思路。目前研究较为广泛的靶向治疗药物包括曲妥珠单抗、拉帕替尼、帕妥珠单抗、TDM1和贝伐珠单抗。

关键词: 乳腺肿瘤, 新辅助化疗

Abstract: Neoadjuvant chemotherapy is one of the common means in multidisciplinary treatment of locally advanced breast cancer, with anthracyclines and taxanes as main chemotherapeutic drugs. In recent years, molecular target agents have significantly improved the efficacy of chemotherapy, as well as have provided more choices and ideas for clinical treatment. Currently, the widely studied molecular targeted drugs include trastuzumab, lapatinib, pertuzumab, TDM1 and bevacizumab.

Key words: Breast neoplasms, Neoadjuvant chemotherapy