国际肿瘤学杂志

国际肿瘤学杂志 ›› 2015, Vol. 42 ›› Issue (2): 147-149.doi: 10.3760/cma.j.issn.1673-422X.2015.02.018

• 综述 • 上一篇    下一篇

混合型小细胞肺癌的临床特点及诊断治疗

门玉,惠周光   

  1. 100021北京协和医学院 中国医学科学院肿瘤医院放疗科
  • 出版日期:2015-02-08 发布日期:2015-02-02
  • 通讯作者: 惠周光 E-mail:drhuizg@163.com

Clinicopathological characteristics, diagnosis and treatment of combined small cell lung cancer

Men Yu, Hui Zhouguang   

  1. Department of Radiation Oncology, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China
  • Online:2015-02-08 Published:2015-02-02
  • Contact: Hui Zhouguang E-mail:drhuizg@163.com

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被引次数

1

摘要： 混合型小细胞肺癌是小细胞肺癌的特殊病理亚型，其发病率和诊断率均较低，但近年来有显著增加趋势。其临床特点与单纯型小细胞肺癌相似，但病变相对局限。治疗以综合治疗为主，但化疗有效率相对较低。其预后与小细胞肺癌相仿，预后因素主要有Karnofsky功能状态评分、临床分期、混合成分、肿瘤位置和大小、手术切缘等。放疗能改善局部晚期、淋巴结阳性或术后淋巴结转移较多患者的生存。

关键词: 诊断, 治疗, 预后, 肺肿瘤

Abstract: Combined small cell lung cancer (CSCLC) is a special subtype of small cell lung cancer (SCLC), which has a low incidence and diagnostic rate. However,  the incidence and diagnostic rate appear an increasing tendency recently. The clinical features of CSCLC are similar to the pure SCLC, while it has a relatively limited stage. The main treatment pattern of CSCLC is multimodality therapy, though the response to chemotherapy in CSCLC is relatively poor. Survival between patients with CSCLC versus SCLC is similar. KPS, stage, composite components, tumor location and diameter, surgery margin are prognostic factors. Radiotherapy can benefit for the patients with ⅢA/ⅢB disease, positive lymph nodes, or with more metastatic lymph nodes after surgery.

Key words: Diagnosis, Therapy, Prognosis, Lung neoplasms