国际肿瘤学杂志

国际肿瘤学杂志 ›› 2014, Vol. 41 ›› Issue (8): 599-602.doi: 10.3760/cma.j.issn.1673-422X.2014.08.013

• 综述 • 上一篇    下一篇

进展期胃癌化疗及分子靶向治疗

裴波, 寸英丽   

  1. 650118昆明医科大学第三附属医院腹部外科
  • 收稿日期:2014-02-25 修回日期:2014-04-15 出版日期:2014-08-15 发布日期:2014-08-14
  • 通讯作者: 寸英丽，E-mail：cunyingli@medmail.com.cn E-mail:cunyingli@medmail.com.cn
  • 基金资助:

    云南省科技厅-昆明医科大学应用基础联合专项(2010cd179)

Chemotherapy and molecular targeted therapy of advanced gastric cancer

Pei  Bo, Cun  Yingli   

  • Received:2014-02-25 Revised:2014-04-15 Online:2014-08-15 Published:2014-08-14
  • Contact: Cun Yingli E-mail:cunyingli@medmail.com.cn

PDF

1301

被引次数

3

摘要： 化疗和分子靶向治疗是不可手术切除胃癌的主要治疗手段。近年来，氟尿嘧啶类、铂类和紫杉类3类胃癌化疗中常用药物通过不断地调整与优化，延长了进展期胃癌患者的生存期，改善了生活质量。分子靶向治疗在胃癌治疗中的应用受到越来越多的关注，已有众多的Ⅲ期临床试验用于评估胃癌分子靶向治疗疗效。化疗及分子靶向治疗的进展为晚期胃癌患者带来了新的希望。

关键词: 胃肿瘤, 药物疗法, 分子靶向治疗

Abstract: Chemotherapy and molecular targeted therapy are the main treatments in unresectable gastric cancer. In recent years, due to the adjustment and optimization of chemotherapy regimens which are consist of fluorouracil, platinum and taxane, the survival time of gastric cancer patient has been prolonged and the quality of life has been improved. The molecular targeted therapy in gastric cancer arouses more and more concern, and there are many phrase Ⅲ clinical trials which are used to assess the efficacy of molecular targeted therapy. The advances of chemotherapy and molecular targeted therapy bring new hope to advanced gastric cancer patients.

Key words: Stomach neoplasms, Drug Therapy, Molecular targeted therapy