国际肿瘤学杂志 ›› 2014, Vol. 41 ›› Issue (3): 184-187.doi: 10.3760/cma.j.issn.1673-422X.2014.03.007

• 综述 • 上一篇    下一篇

恶性肿瘤放化疗致乙型肝炎病毒再激活防治进展

汪孟森, 于甬华   

  1. 250117 济南,山东省肿瘤医院放疗二科 济南大学山东省医学科学院医学与生命科学学院
  • 出版日期:2014-03-08 发布日期:2014-03-17
  • 通讯作者: 于甬华,E-mail:sdyonghuayu@163.com E-mail:sdyonghuayu@163.com

Progress of prevention and cure of chemoradiotherapy-related hepatitis B virus reactivation

WANG  Meng-Sen, YU  Yong-Hua   

  1. Second Department of Radiation Oncology, Shandong Cancer Hospital; School of Medicine and Life Sciences, University of Ji′nanShandong Academy of Medical Sciences, Ji′nan 250117, China
  • Online:2014-03-08 Published:2014-03-17
  • Contact: Yu Yonghua, E-mail: sdyonghuayu@163.com E-mail:sdyonghuayu@163.com

摘要: 乙型肝炎病毒感染者接受放化疗时可能出现病毒再激活,引起急性肝功能损伤。预防性抗病毒治疗可以减少病毒再激活及其相关病的发生,但尚缺乏统一的应用规范,因此需要多学科合作并开展更多前瞻性研究,以明确抗病毒治疗的个体化方案。

关键词: 肝炎病毒, 乙型, 病毒激活, 肿瘤, 药物疗法, 放射疗法

Abstract: Reactivation of hepatitis B virus (HBV) in cancer patients with HBV infection during or after chemoradiotherapy can lead to acute liver injury, even death. Antiviral prophylaxis can reduce the occurrence of HBV reactivation and its associated morbidity. However, there is no unified standard to guide antiviral treatment. Therefore, multidisciplinary collaboration and more prospective study should be carried out to identify the individual antiviral treatment plan.

Key words: Hepatitis B virus, Virus activation, Neoplasms, Drug therapy, Radiotherapy