maspin基因与肿瘤靶向治疗

doi:10.3760/cma.j.issn.1673-422X.2014.01.007

摘要/Abstract

摘要： maspin是一种抑癌基因，属于丝氨酸蛋白酶抑制剂超家族成员，能抑制肿瘤细胞生长、侵袭和转移，促进肿瘤细胞凋亡，影响肿瘤血管生成以及增加化疗敏感性。对maspin靶向治疗肿瘤的机制深入研究可为肿瘤治疗提供新的思路。

Abstract: Maspin, a member of the serine protease inhibitor superfamily, is considered to be a tumor suppressor. Maspin can inhibit the tumor cells growth, invasion and metastasis, promote apoptosis of the tumor cells, affect tumor angiogenesis and increase the sensitivity of chemotherapy. The indepth study of the target therapy mechanisms of maspin can provide new ideas for tumor treatment.

Key words: Genes, Neoplasms, Target therapy

曹玲, 钱亚云, 刘延庆. maspin基因与肿瘤靶向治疗[J]. 国际肿瘤学杂志, 2014, 41(1): 21-23.

Cao Ling, Qian Yayun, Liu Yanqing. Maspin and target therapy of tumor[J]. Journal of International Oncology, 2014, 41(1): 21-23.

参考文献

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