血小板内皮细胞黏附分子-1与肿瘤

doi:10.3760/cma.j.issn.1673422X.2014.01.002

国际肿瘤学杂志 ›› 2014, Vol. 41 ›› Issue (1): 4-7.doi: 10.3760/cma.j.issn.1673422X.2014.01.002

血小板内皮细胞黏附分子-1与肿瘤

刘芳, 贾晓艳, 王若雨

116001大连大学附属中山医院肿瘤内科（刘芳、王若雨）；大连大学附属新华医院病理科（贾晓艳）

出版日期:2014-01-08 发布日期:2014-01-22
通讯作者: 王若雨，E-mail：wry1963@sohu.com E-mail:wry1963@sohu.com
基金资助:
国家自然科学基金（30970869）

Plateletendothelial cell adhesion molecule1 and tumor

LIU Fang, JIA Xiao-Yan, WANG Ruo-Yu

Department of Oncology, Affiliated Zhongshan Hospital of Dalian University, Dalian 116001, China

Online:2014-01-08 Published:2014-01-22

摘要/Abstract

摘要： 血小板内皮细胞黏附分子1（PECAM1）是免疫球蛋白超家族中的一种黏附分子，高表达于内皮细胞。近年来研究发现，PECAM1与肿瘤的发生、血管生成、细胞凋亡以及耐药均相关，可能对肿瘤的诊断与治疗产生重要影响。

关键词: 抗原, CD31, 肿瘤, 新生血管化, 病理性, 细胞凋亡, 抗药性, 肿瘤

Abstract: Plateletendothelial cell adhesion molecule1 (PECAM1) is a adhesion molecule of the immunoglobulin superfamily, which is highly expressed in endothelial cells. Recent studies show that PECAM1 is related with tumorigenesis, angiogenesis, apoptosis and drug resistance, which may exert a significant influence on the diagnosis and treatment of tumor.

Key words: Antigens, CD31, Neoplasms, Neovascularization, pathologic, Apoptosis, Drug resistance, neoplasm

刘芳, 贾晓艳, 王若雨. 血小板内皮细胞黏附分子-1与肿瘤[J]. 国际肿瘤学杂志, 2014, 41(1): 4-7.

LIU Fang, JIA Xiao-Yan, WANG Ruo-Yu. Plateletendothelial cell adhesion molecule1 and tumor[J]. Journal of International Oncology, 2014, 41(1): 4-7.

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血小板内皮细胞黏附分子-1与肿瘤

Plateletendothelial cell adhesion molecule1 and tumor

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