国际肿瘤学杂志

国际肿瘤学杂志 ›› 2013, Vol. 40 ›› Issue (10): 755-758.

• 综述 • 上一篇    下一篇

局部晚期非小细胞肺癌同步放化疗的研究

黄德波, 肖宝荣   

  1. 271000 泰安市肿瘤防治院放疗科
  • 出版日期:2013-10-08 发布日期:2013-09-23
  • 通讯作者: 肖宝荣，E-mail：hdbysfl@163.com E-mail:hdbysfl@163.com

Concurrent chemoradiation for non-small cell lung cancer

HUANG  De-Bo, XIAO  Bao-Rong   

  1. Department of Radiation Oncology, Taian Tumor Hospital, Taian 271000, China
  • Online:2013-10-08 Published:2013-09-23
  • Contact: XIAO Bao-rong, E-mail: hdbysfl@163.com E-mail:hdbysfl@163.com

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摘要： 局部晚期非小细胞肺癌（NSCLC）非手术治疗的标准手段为同步放化疗。同步放化疗中常用的化疗方案有EP方案、NP方案、DC方案及PC方案。新药联合方案及靶向治疗目前仍处于研究阶段。老年患者的耐受性下降，但并非同步放化疗的绝对禁忌人群。超分割及高剂量放疗虽然耐受性尚可，但其有效性及远期不良反应仍需进一步研究和评估。

关键词: 肺肿瘤, 放射疗法, 药物疗法

Abstract: The standard non-surgery approach for locally advanced non-small cell lung cancer (NSCLC) is concurrent chemoradiotherapy. Common chemotherapy regimens include EP, NP, DC and PC. New chemotherapy drugs combination and targeted therapy are still under study. The tolerances of elderly patients are declining for concurrent chemoradiotherapy, but it is not the absolute contraindication. The tolerance for hyperfraction and high dose radiotherapy is well, however, the effectiveness and long-term toxicity need to be further studied and evaluated.

Key words: Lung neoplasms, Radiotherapy, Drug therapy