国际肿瘤学杂志 ›› 2013, Vol. 40 ›› Issue (5): 377-380.

• 综述 • 上一篇    下一篇

急性白血病的耐药机制及对策

杨璐璐, 刘欣   

  1. 230001合肥,安徽医科大学附属省立医院血液科
  • 出版日期:2013-05-08 发布日期:2013-05-15
  • 通讯作者: 刘欣 E-mail:liuxinhf@yahoo.com.cn

Resistance mechanisms and the countermeasures of acute leukemia

YANG  Lu-Lu, LIU  Xin   

  1. Department of Hematology, Provincial Hospital of Anhui Medical University,  Hefei 230001, China

  • Online:2013-05-08 Published:2013-05-15
  • Contact: LIU Xin E-mail:liuxinhf@yahoo.com.cn

摘要: 急性白血病(AL)是一类造血干细胞异常的克隆性恶性疾病,化疗是其主要的治疗方法,但化疗耐药已经成为成功治疗AL的主要障碍,经常会有一系列的药物共同发生耐药,即多药耐药。

关键词: 白血病, 多药耐药相关蛋白质类

Abstract: Acute leukemia (AL) is a malignant disease of clonal hematopoietic stem cell abnormalities. Chemotherapy is the main method for the treatment of AL, but the chemotherapy drug resistance has become a major obstacle to successful treatment. There is often a series of drug cooccurrence of drug resistance, and that is multidrug resistance.

Key words: Leukemia, Multidrug resistance-associated proteins