国际肿瘤学杂志 ›› 2013, Vol. 40 ›› Issue (2): 100-102.

• 综述 • 上一篇    下一篇

肿瘤相关基因PFTK1

朱军, 岳文涛   

  1. 101149 首都医科大学附属北京胸科医院结核病胸部肿瘤研究所细胞室
  • 出版日期:2013-02-08 发布日期:2013-01-25
  • 通讯作者: 岳文涛,E-mail:yuewt2000@yahoo.com E-mail:yuewt2000@yahoo.com

Tumor associated gene PFTK1

ZHU  Jun, YUE  Wen-Tao   

  1. Corresponding author: YUE Wen-tao, E-mail: yuewt2000@yahoo.com
  • Online:2013-02-08 Published:2013-01-25
  • Contact: Corresponding author: YUE Wen-tao, E-mail: yuewt2000@yahoo.com E-mail:yuewt2000@yahoo.com

摘要: PFTK1是细胞周期蛋白依赖性激酶Cdc2家族重要成员,在多种恶性肿瘤中过表达,参与细胞周期、肿瘤的侵袭和转移、Wnt信号通路的调控等多个过程,对肿瘤的预后有重要影响。

关键词: PFTK1, 细胞周期, 肿瘤转移, Wnt信号通路, 预后

Abstract: PFTK1, an important member of cyclin dependent kinase Cdc2 family, is over expressed in many malignancies. PFTK1 involves in multiple processes, such as regulation of cell cycle, tumor invasion and metastasis, and the Wnt signal transduction pathway, which has a significant impact on prognosis of tumor.

Key words: PFTK1, Cell cycle, Neoplasms metastasis, Wnt signal pathway, Prognosis