关键词: 树突细胞, 转染, 肿瘤, 免疫疗法

Abstract: Dendritic cells is the most powerful professional antigen presenting cells in vivo. In recent years, DC vaccine has become one of the research hotspots in tumor treatment. DC vaccine which is modified by varieties of genes can solve antigens dissociation and tumor immune escape and so on caused by the weak tumor cell immunogenicity and lower DC antigen commission ability, and can induce stronger antitumor immune response, which can achieve inhibitory tumor, reduce tumor effect and brings new hope for patients with tumor.

Key words: Dendritic cells, Transfection, Neoplasms, Immunotherapy