肠道微生态与造血干细胞移植相关性中国专家共识（2026版）

doi:10.3760/cma.j.cn371439-20260308-00064

摘要/Abstract

摘要：

造血干细胞移植（HSCT）会影响肠道菌群稳态，而肠道微生态也可能通过多种机制影响HSCT患者的预后。为了更深入地了解肠道微生态与HSCT相关性的关键问题，并学习和吸收最新的研究进展，中国抗癌协会肿瘤与微生态委员会组织相关专家在《肠道微生态与造血干细胞移植相关性中国专家共识》（2021版）的基础上进行修订，提出了《肠道微生态与造血干细胞移植相关性中国专家共识（2026版）》，本共识参照国内外最新文献，结合学科内的最新技术和研究，针对肠道微生态在造血干细胞移植的适应证等问题提出9条推荐意见，供临床医生在实践中参考。该共识既可为临床医生提供实践指导，也为肿瘤与微生态领域的进一步深入研究奠定了基础。

关键词: 胃肠道微生物组, 造血干细胞移植, 多数赞同, 相关性

Abstract:

Hematopoietic stem cell transplantation （HSCT） affects intestinal flora homeostasis， and intestinal microecology may also affect the prognosis of HSCT patients through multiple mechanisms. To gain a deeper understanding of intestinal microecology and HSCT to address the key issues of correlation， and to learn and absorb the latest research progress， the Tumor and Microecology Committee of the Chinese Anti-Cancer Association organized relevant experts to revise on the basis of the "Chinese expert consensus on the correlation between intestinal microecology and hematopoietic stem cell transplantation " （2021 Edition） and proposed the "Chinese expert consensus on the correlation between intestinal microecology and hematopoietic stem cell transplantation （2026 Edition）". This consensus， based on the latest domestic and international literature and combined with the latest technology and research in the discipline， presents 9 recommendations regarding issues such as the indications of intestinal microecology in hematopoietic stem cell transplantation， for clinicians to refer to in practice. This consensus can not only provide practical guidance for clinicians， but also lay a foundation for further in-depth research in the fields of oncology and microecology.

Key words: Gastrointestinal microbiome, Hematopoietic stem cell transplantation, Consensus, Correlation

中国抗癌协会肿瘤与微生态专业委员会. 肠道微生态与造血干细胞移植相关性中国专家共识（2026版）[J]. 国际肿瘤学杂志, 2026, 53(7): 388-397.

Tumor and Microecology Committee of the Chinese Anti-Cancer Association. Chinese expert consensus on the correlation between intestinal microecology and hematopoietic stem cell transplantation （2026 Edition）[J]. Journal of International Oncology, 2026, 53(7): 388-397.

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