TACE联合靶向、免疫治疗在BCLC B/C期肝细胞癌中的应用

doi:10.3760/cma.j.cn371439-20220520-00107

摘要/Abstract

摘要：

经动脉化疗栓塞（TACE）是巴塞罗那临床肝癌（BCLC）分期系统B期肝细胞癌（HCC）的标准治疗方法。但TACE存在一定的局限性,TACE联合系统治疗或许更能使BCLC B/C期HCC患者获益。探索TACE分别联合靶向治疗、免疫治疗及靶向+免疫治疗BCLC B/C期HCC的疗效及安全性,将为HCC的临床治疗提供新的思路。

关键词: 癌,肝细胞, 化学栓塞,治疗性, 分子靶向治疗, 免疫疗法, 综合疗法

Abstract:

Transcatheter arterial chemoembolization （TACE） is the standard treatment for Barcelona Clinic Liver Cancer （BCLC） stage B hepatocellular carcinoma （HCC）. However, TACE has some limitations, TACE combined with systemic therapy may be more beneficial to patients with BCLC stage B/C HCC. To explore the efficacy and safety of TACE combined with molecular targeted therapy, immunotherapy and molecular targeted therapy + immunotherapy in the treatment of B/C stage HCC of BCLC will provide new ideas for the clinical treatment of HCC.

Key words: Carcinoma, hepatocellular, Chemoembolization, therapeutic, Molecular targeted therapy, Immunotherapy, Combined modality therapy

宋佳, 胡钦勇. TACE联合靶向、免疫治疗在BCLC B/C期肝细胞癌中的应用[J]. 国际肿瘤学杂志, 2022, 49(9): 550-554.

Song Jia, Hu Qinyong. Application of TACE combined with molecular targeted therapy and immunotherapy in BCLC B/C hepatocellular carcinoma[J]. Journal of International Oncology, 2022, 49(9): 550-554.

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