国际肿瘤学杂志 ›› 2020, Vol. 47 ›› Issue (10): 611-614.doi: 10.3760/cma.j.cn371439-20200311-00087

• 综述 • 上一篇    下一篇

FAM3基因家族在肿瘤中的作用

廖成成1, 安家兴2, 谭张雪1, 王倩3(), 刘建国1,3()   

  1. 1遵义医科大学口腔医学院 563006
    2遵义医科大学附属医院消化内科 563000
    3贵州省普通高等学校口腔疾病研究特色重点实验室,遵义 563006
  • 收稿日期:2020-03-11 修回日期:2020-04-27 出版日期:2020-10-08 发布日期:2020-11-20
  • 通讯作者: 王倩,刘建国 E-mail:qianwang07@126.com;jgl_zmu@126.com
  • 基金资助:
    贵州省普通高等学校科技拔尖人才支持计划(黔教合KY字)(2016-080)

Role of FAM3 gene family in tumor

Liao Chengcheng1, An Jiaxing2, Tan Zhangxue1, Wang Qian3(), Liu Jianguo1,3()   

  1. 1School of Stomatology, Zunyi Medical University, Zunyi 563006, China
    2Department of Gastroenterology, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, China
    3Special Key Laboratory of Oral Disease Research, Higher Education Institution in Guizhou Province, Zunyi Medical University, Zunyi 563006, China
  • Received:2020-03-11 Revised:2020-04-27 Online:2020-10-08 Published:2020-11-20
  • Contact: Wang Qian,Liu Jianguo E-mail:qianwang07@126.com;jgl_zmu@126.com
  • Supported by:
    Scientific Talent Fund of Guizhou College(2016-080)

摘要:

序列相似家族3(FAM3)基因家族与人类肿瘤关系密切,其在糖脂代谢及血管再生等方面具有重要作用,与食管鳞状细胞癌、胃癌、结肠癌、胰腺癌、口腔鳞状细胞癌和乳腺癌的发生发展相关。分析FAM3基因家族在糖脂代谢及肿瘤中的作用对于认识人类肿瘤的发生发展具有重要意义。

关键词: 肿瘤, 糖脂代谢, FAM3基因家族

Abstract:

Family with sequence similarity 3 (FAM3) gene family is closely related to human tumors, and plays an important role in glucose and lipid metabolism and angiogenesis, and it is related to the occurrence and development of esophageal squamous cell carcinoma, gastric cancer, colon cancer, pancreatic cancer, oral squamous cell carcinoma and breast cancer. Analysis of the role of the FAM3 gene family in glycolipid metabolism and tumors may be of great significance for understanding the occurrence and development of human tumors.

Key words: Neoplasms, Glycolipid metabolism, Family with sequence similarity 3