食管鳞状细胞癌免疫治疗进展

doi:10.3760/cma.j.cn371439-20200708-00082

摘要/Abstract

摘要：

随着免疫治疗在临床应用中的拓展,其在食管鳞状细胞癌(ESCC)治疗中的价值也得以显现。程序性死亡蛋白-1(PD-1)及其配体PD-L1、细胞毒性T淋巴细胞抗原4等免疫检查点抑制剂在晚期ESCC的免疫治疗中展现出良好的抗肿瘤活性和安全性。

关键词: 食管肿瘤, 免疫疗法, T淋巴细胞,细胞毒性, 程序性死亡蛋白-1, 免疫检查点抑制剂

Abstract:

With the development of immunotherapy in clinical application, immunotherapy also takes advantage in esophageal squamous cell carcinoma (ESCC). Immune checkpoint inhibitors such as programmed death-1 (PD-1) and its ligand PD-L1 and cytotoxic T lymphocyte antigen-4 show significant antitumor activity and safety in immunotherapy for patients with advanced ESCC.

Key words: Esophageal neoplasms, Immunotherapy, T-lymphocytes,cytotoxic, Programmed death-1, Immune checkpoint inhibitor

杨文倩, 黄俊星. 食管鳞状细胞癌免疫治疗进展[J]. 国际肿瘤学杂志, 2021, 48(7): 429-432.

Yang Wenqian, Huang Junxing. Research progress of immunotherapy in esophageal squamous cell carcinoma[J]. Journal of International Oncology, 2021, 48(7): 429-432.

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