新型抗氧化剂在泌尿系统肿瘤中的研究进展

doi:10.3760/cma.j.issn.1673-422X.2019.01.012

国际肿瘤学杂志 ›› 2019, Vol. 46 ›› Issue (1): 54-56.doi: 10.3760/cma.j.issn.1673-422X.2019.01.012

新型抗氧化剂在泌尿系统肿瘤中的研究进展

宋家瑞¹,张斌¹,杨中文²,徐保才²,王超²,马鸣²

¹济南大学山东省医学科学院医学与生命科学学院 250062； ²山东省济宁市第一人民医院泌尿外科 272011

收稿日期:2018-09-21 出版日期:2019-01-08 发布日期:2019-04-03
通讯作者: 马鸣 E-mail:ming_ma66@126.com

Research progress of new antioxidants in urological neoplasms

Song Jiarui¹, Zhang Bin¹, Yang Zhongwen², Xu Baocai², Wang Chao², Ma Ming²

¹School of Medicine and Life Sciences, University of JinanShandong Academy of Medical Sciences, Jinan 250062, China; ²Department of Urological Surgery, Jining First People′s Hospital of Shandong Province, Jining 272011, China

Received:2018-09-21 Online:2019-01-08 Published:2019-04-03
Contact: Ma Ming E-mail:ming_ma66@126.com

摘要/Abstract

摘要： 抗氧化剂是机体防御氧化应激的重要物质，能够通过减少细胞内活性氧的含量维持体内氧化还原物质的平衡。研究表明新型抗氧化剂能抑制肿瘤细胞增殖、诱导凋亡、抑制血管生成及抑制肿瘤细胞的转移，对多种泌尿系统肿瘤生长具有明显的抑制作用。抗氧化剂在泌尿系统肿瘤的预防及治疗中极具应用价值，有望成为抗肿瘤新药。

关键词: 抗氧化剂, 活性氧, 泌尿系肿瘤

Abstract: Antioxidants are important substances in the body against oxidative stress, which can maintain the balance of redox substances by reducing the content of reactive oxygen species in cells. Studies have shown that new antioxidants have significant inhibitory effects on the growth of urological neoplasms by inhibiting tumor cell proliferation, inducing apoptosis, disturbing angiogenesis and metastasis of tumor cells. Antioxidants are of great value in the prevention and treatment of urinary system tumors and are expected to become new antitumor drugs.

Key words: Antioxidants, Reactive oxygen species, Urologic neoplasms

宋家瑞,张斌,杨中文,徐保才,王超,马鸣. 新型抗氧化剂在泌尿系统肿瘤中的研究进展[J]. 国际肿瘤学杂志, 2019, 46(1): 54-56.

Song Jiarui, Zhang Bin, Yang Zhongwen, Xu Baocai, Wang Chao, Ma Ming. Research progress of new antioxidants in urological neoplasms[J]. Journal of International Oncology, 2019, 46(1): 54-56.

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新型抗氧化剂在泌尿系统肿瘤中的研究进展

Research progress of new antioxidants in urological neoplasms

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