国际肿瘤学杂志 ›› 2018, Vol. 45 ›› Issue (2): 122-125.doi: 10.3760/cma.j.issn.1673422X.2018.02.015

• 综述 • 上一篇    下一篇

液体活检在上皮性卵巢癌诊治中的应用

唐慧芸,莫小雨,白莉平,郑艾   

  1. 610041 成都,四川大学华西第二医院妇产科 四川大学出生缺陷与相关妇儿疾病教育部重点实验室   
  • 出版日期:2018-02-08 发布日期:2018-02-28
  • 通讯作者: 郑艾,Email: 894591422@qq.com E-mail:894591422@qq.com

Application of liquid biopsies in diagnosis and treatment of epithelial ovarian cancer

Tang Huiyun, Mo Xiaoyu, Bai Liping, Zheng Ai   

  1. Department of Obsterics and Gynecology, West China Second Hospital, Sichuang University; Key Laboratory of Birth Defects and Related Disease of Women and Children (Sichuan University), Ministry of Education, Chengdu 610041, China
  • Online:2018-02-08 Published:2018-02-28
  • Contact: Zheng Ai E-mail:894591422@qq.com

摘要: 液体活检已在恶性肿瘤研究领域取得重大进展,循环肿瘤细胞、循环肿瘤DNA、外泌体等可作为生物标志物用于上皮性卵巢癌的检测、动态监测病情变化、判断患者预后、评估化疗药物耐药性等,可为患者制定个体化的治疗方案提供依据,实现上皮性卵巢癌的精准医疗。

关键词: 卵巢肿瘤, 液体活检

Abstract: Liquid biopsies have made a great progress in malignant tumors research. Circulating tumor cells, circulating tumor DNA and exosomes can be regarded as biomarkers to be applied in diagnosis of epithelial ovarian cancer, monitoring progress dynamically, estimating prognosis and drug resistance in chemotherapy, which can help doctors provide patients with individual treatment to realize precision medicine in epithelial ovarian cancer.

Key words: Ovarian neoplasms, Liquid biopsy