国际肿瘤学杂志 ›› 2014, Vol. 41 ›› Issue (2): 87-90.doi: 10.3760/cma.j.issn.1673-422X.2014.02.003

• 综述 • 上一篇    下一篇

高良姜素抗肿瘤作用

苏丽娟,张海涛,伍俊   

  1. 524023 湛江,广东医学院生物化学与分子生物学教研室(苏丽娟、张海涛),呼吸疾病研究所(伍俊)
  • 收稿日期:2013-09-05 修回日期:2013-12-28 出版日期:2014-02-08 发布日期:2014-01-26
  • 通讯作者: 伍俊,E-mail: wujun0294@sina.com E-mail:wujun0294@sina.com
  • 基金资助:

    广东省中医药管理局项目(20111239);国家自然科学基金(81273549)

Anti-tumor effects of galangin

Su Lijuan, Zhang Haitao, Wu Jun   

  1. Department of Biochemistry and Molecular Biology, Guangdong Medical College, Zhanjiang 524023, China
  • Received:2013-09-05 Revised:2013-12-28 Online:2014-02-08 Published:2014-01-26
  • Contact: Wu Jun E-mail:wujun0294@sina.com

摘要: 高良姜素是一种从高良姜的根茎中提取的天然黄酮类化合物,是高良姜中重要的药用成分。大量研究表明,高良姜素具有多种生物活性,发现它有多种抗肿瘤机制,包括抗增殖、促凋亡、促自噬、以及抑制肿瘤细胞的转移等。

关键词: 高良姜素, 抗肿瘤, 细胞凋亡, 自噬

Abstract: Galangin is a natural flavonoid, extracted from the root of galangal, and it is an important medical composition of galangal. A lot of researches show that galangin possesses various biological activities, researchers also find it has many antitumor mechanisms, including inhibiting proliferation, promoting apoptosis, accelerating autophagy and inhibiting metastasis of tumor cells.

Key words: Galangin, Antitumor, Apoptosis, Autophagy