国际肿瘤学杂志

国际肿瘤学杂志 ›› 2013, Vol. 40 ›› Issue (8): 595-597.

• 综述 • 上一篇    下一篇

非小细胞肺癌患者恶性胸腔积液中EGFR基因突变

楚慧丽, 梁秀菊, 毕经旺   

  1. 250031济南军区总医院肿瘤科
  • 出版日期:2013-08-08 发布日期:2013-08-15
  • 通讯作者: 毕经旺，E-mail: jingwangbi@live.cn E-mail:jingwangbi@live.cn

EGFR mutation in malignant pleural effusion of non-small cell lung cancer

CHU  Hui-Li, LIANG  Xiu-Ju, BI  Jing-Wang   

  1. Department of Oncology, General Hospital, Jinan Command of the People’s Liberation Army, Jinan 250031, China
  • Online:2013-08-08 Published:2013-08-15
  • Contact: Corresponding author: BI Jing-wang, E-mail: jingwangbi@live.cn E-mail:jingwangbi@live.cn

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被引次数

1

摘要： 非小细胞肺癌患者接受表皮生长因子受体-酪氨酸激酶抑制剂 (EGFR-TKI)治疗前进行EGFR检测已经成为共识。恶性胸腔积液是非小细胞肺癌 (NSCLC)患者常见的临床表现，采用不同方法对胸腔积液细胞及游离核酸提取后进行EGFR检测，对预测EGFR-TKI的疗效有着良好前景。

关键词: 癌, 非小细胞肺, 受体, 表皮生长因子, 突变, 恶性胸腔积液

Abstract: EGFR testing has become the consensus before EGFR-TKI treatment in non-small cell lung cancer patients. Malignant pleural effusion is the common clinical manifestation in NSCLC patients, and   EGFR testing by using different methods in pleural effusion cells and free nucleic acids has good prospect for predicting the efficacy of EGFR-TKI.

Key words: Carcinoma, non-small cell lung, Receptor, epidermal growth factor, Mutation, Malignant pleural effusion