国际肿瘤学杂志 ›› 2013, Vol. 40 ›› Issue (2): 145-148.

• 综述 • 上一篇    下一篇

妊娠合并宫颈癌的诊治及预后

强素凤, 黄勇   

  1. 200030 上海交通大学医学院附属国际和平妇幼保健院妇科
  • 出版日期:2013-02-08 发布日期:2013-01-25
  • 通讯作者: 黄勇,E-mail: drhuangyong@yahoo.com.cn E-mail:drhuangyong@yahoo.com.cn

Diagnosis, treatment and prognosis of uterine cervical neoplasms complicated with pregnancy

QIANG  Su-Feng, HUANG  Yong   

  1. Department of Gynaecology, International Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China

  • Online:2013-02-08 Published:2013-01-25
  • Contact: Corresponding author: HUANG Yong, E-mail: drhuangyong@yahoo.com.cn E-mail:drhuangyong@yahoo.com.cn

摘要: 妊娠合并宫颈癌的发生率随生育年龄推迟而呈上升趋势。由于妊娠早期细胞学筛查的普及,妊娠合并宫颈癌多被早期发现。细胞学异常患者必须行阴道镜检查,必要时行宫颈活检。宫颈锥切术仅用于排除浸润癌。孕12周前诊断的宫颈浸润癌需及时治疗;孕12周后诊断的宫颈浸润癌如为早期,可待胎儿成熟后延迟治疗。可使用新辅助化疗以稳定患者病情至胎儿分娩。妊娠合并宫颈癌治疗需依据临床分期、孕周及患者是否有继续妊娠的意愿,制定个性化方案。妊娠合并宫颈癌多为早期浸润癌,预后较好。

关键词: 宫颈肿瘤, 妊娠, 诊断, 治疗, 预后

Abstract: The incidence of cervical neoplasms complicated with pregnancy is rising, with delaying of reproductive age. Because of the prevalence of cytology in pregnancy, cervical neoplasms complicated with pregnancy are mostly detected early. All patients with cytological abnormalities should undergo colposcopy, and when necessary, they should undergo cervical biopsy. Conization is reserved for patients with suspected invasion. In cases of invasive carcinoma detected up to the 12th week of pregnancy, immediate treatment is prioritized. Regarding diagnoses made during the second trimester, in early-stage invasive cancers, delay of therapy seems to be safe, fetal pulmonary maturity can be awaited. And the use of neoadjuvant chemotherapy to stabilize the disease until the time of delivery appears to be viable. Doctors should draw up personalized program for the patients with cervical neoplasms complicated with pregnancy according to stage of disease, gestational weeks and the patient’s desire for continued pregnancy. Cervical neoplasms complicated with pregnancy are mostly early-stage invasive cancers, so prognosis is good.

Key words: Uterine cervical neoplasms, Pregnancy, Diagnosis, Therapy, Prognosis