国际肿瘤学杂志 ›› 2013, Vol. 40 ›› Issue (2): 114-117.

• 综述 • 上一篇    下一篇

白藜芦醇抗乳腺癌的多靶点机制

仇凤启, 丁晓超, 马萍   

  1. 110001 沈阳, 中国医科大学第一医院肿瘤研究所2(仇凤启、马萍),吉林省肝胆病医院(丁晓超)

  • 出版日期:2013-02-08 发布日期:2013-01-25
  • 通讯作者: 马萍,E-mail: pingm12@hotmail.com E-mail:pingm12@hotmail.com
  • 基金资助:

    辽宁省教育厅基金(L2012281)

Multiple molecular targets of resveratrol: anti-breast cancer mechanisms

CHOU  Feng-Qi, DING  Xiao-Chao, MA  Ping   

  1. Institute of Oncology, the First Affiliated Hospital, China Medical University, Shenyang 110001, China
  • Online:2013-02-08 Published:2013-01-25
  • Contact: Corresponding author: MA Ping, E-mail: pingm12@hotmail.com E-mail:pingm12@hotmail.com

摘要: 白藜芦醇是从植物中提取的多酚类活性物质,具有抗炎、抗氧化、抗肿瘤等多种作用。研究表明,白藜芦醇能作用于乳腺癌多种分子靶点,发挥抑制乳腺癌细胞增殖进而促进其凋亡的作用,为白藜芦醇应用于乳腺癌的治疗提供了理论依据。

关键词: 白藜芦醇, 乳腺肿瘤, 细胞凋亡

Abstract: Resveratrol, which is produced by natural plants, has various biological activities, including anti-inflammatory, antioxidant and anticancer properties. Recently, it is found that resveratrol can inhibit the proliferation and promote the apoptosis of breast cancer through multiple molecular targets, which provides a theoretical basis for resveratrol used in the treatment of breast cancer.

Key words: Resveratrol, Breast neoplasms, Apotosis