国际肿瘤学杂志

国际肿瘤学杂志 ›› 2014, Vol. 41 ›› Issue (6): 454-457.doi: 10.3760/cma.j.issn.1673422X.2014.06.016

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微小RNA在胰腺癌侵袭转移中的作用及机制

张伟,陈国栋,贺更生,李翀   

  1. 421001衡阳，南华大学附属第一医院普外科
  • 出版日期:2014-06-08 发布日期:2014-05-08
  • 通讯作者: 贺更生, Email: hgs_china@163.com E-mail:hgs_china@163.com
  • 基金资助:

    湖南省科技厅计划项目（2012FJ3105）

The effect and mechanism of microRNA in the invasion and metastasis of pancreatic cancer

 ZHANG  Wei, CHEN  Guo-Dong, HE  Geng-Sheng, LI  Chong   

  1. Department of General Surgery, First Affiliated Hospital of University of South China, Hengyang 421001, China
  • Online:2014-06-08 Published:2014-05-08
  • Contact: He Gengsheng E-mail:hgs_china@163.com

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被引次数

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摘要： 特异性微小RNA（miRNA）的异常表达与胰腺癌的发生、发展及预后相关，是其侵袭转移的潜在预测目标，且与胰腺癌侵袭转移相关生物学特性存在密切联系。因此miRNA有望成为胰腺癌侵袭转移机制研究的新靶点。

关键词: 胰腺肿瘤, 微RNAs, 肿瘤侵润, 肿瘤转移

Abstract: Evidence has shown that the abnormal expression of specific microRNAs（miRNAs） is associated with the occurrence, development and prognosis of pancreatic cancer, which is the potential target of forecast about invasion and metastasis of pancreatic cancer. There is  close relation between miRNAs and biological characteristics of pancreatic cancer invasion and metastasis. Therefore, miRNAs are expected to become the new research targets of the mechanism of invasion and metastasis of pancreatic cancer.

Key words: 胰腺肿瘤, 微RNAs, 肿瘤侵润, 肿瘤转移