国际肿瘤学杂志

国际肿瘤学杂志 ›› 2017, Vol. 44 ›› Issue (1): 71-74.doi: 10.3760/cma.j.issn.1673-422X.2017.01.019

• 综述 • 上一篇    下一篇

胃肠道肿瘤的靶向治疗

黄炎,程丹,杨继元   

  1. 434000 荆州，长江大学附属第一医院肿瘤科（黄炎、杨继元）；长江大学第二临床医学院（程丹）
  • 出版日期:2017-01-08 发布日期:2016-12-07
  • 通讯作者: 杨继元，Email: yangjiyuanchina@163.com E-mail:yangjiyuanchina@163.com

Targeted therapies for gastrointestinal cancer

Huang Yan, Cheng Dan, Yang Jiyuan   

  1. Department of Oncology, First Affiliated Hospital of Yangtze University, Jingzhou 434000, China
  • Online:2017-01-08 Published:2016-12-07
  • Contact: Yang Jiyuan, Email: yangjiyuanchina@163.com E-mail:yangjiyuanchina@163.com

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摘要： 分子靶向治疗在晚期胃肠道肿瘤的治疗中有着重要地位。近年来，已研发了大量的靶向治疗药物并进入了临床试验，以验证其疗效和安全性。各期临床试验均证实，以单克隆抗体和酪氨酸激酶抑制剂为代表的靶向治疗药物有着更好的疗效以及安全性。

关键词: 胃肠肿瘤, 抗体, 单克隆, 酪氨酸激酶抑制剂, 靶向治疗

Abstract: Molecular targeted therapy plays an important role in the treatment of gastrointestinal cancer. In recent years, a large number of targeted drugs have been developed and tested in clinical trials to verify their efficacy and security. The better efficacy and security of targeted drugs represented by monoclonal antibodies and tyrosine kinase inhibitors have been demonstrated in each phase of clinical trials.

Key words: Gastrointestinal neoplasms, Antibodies, monclonal, Tyrosine kinase inhibitors, Targeted therapy