国际肿瘤学杂志 ›› 2016, Vol. 43 ›› Issue (1): 49-52.doi: 10.3760/cma.j.issn.1673-422X.2016.01.014

• 综述 • 上一篇    下一篇

食管癌根治性同步放化疗

刘永萱, 冯笑山   

  1. 471000 洛阳,河南科技大学第一附属医院肿瘤科
  • 收稿日期:2015-07-27 出版日期:2016-01-08 发布日期:2015-12-03
  • 通讯作者: 冯笑山 E-mail:samfeng137@hotmail.com

Radical concurrent chemoradiotherapy for esophageal carcinoma

Liu Yongxuan, Feng Xiaoshan   

  1. Department of Oncology, First Affiliated Hospital of He′nan University of Science and Technology, Luoyang 471000, China
  • Received:2015-07-27 Online:2016-01-08 Published:2015-12-03
  • Contact: Feng Xiaoshan E-mail:samfeng137@hotmail.com

摘要: 美国国家综合癌症网络指南指出,对于ⅠB~ⅢA期食管癌患者可行根治性PF方案(顺铂+5氟尿嘧啶)同步放化疗。国内外一些学者对PF方案及放疗剂量作了进一步优化研究,提高了局部控制率和生存率,不良反应在可控范围内。近年来一些新药如卡培他滨、紫杉醇、多西他赛、培美曲塞、卡铂等在根治性同步放化疗中也显示出其优势。

关键词: 食管肿瘤, 放射疗法, 药物疗法, 卡培他滨

Abstract: In National Comprehensive Cancer Network guideline, patients with the clinical stages of ⅠBⅢA esophageal neoplasms should be given radical PF regimen (cisplatin + 5fluorouracil) concurrent chemoradiotherapy. The majorization PF and radiation dosage are studied by some scholars in China and abroad, and the local control rate and survival rate are improved, adverse reaction is within a controllable range. In recent years, some new drugs such as capecitabine, paclitaxel, docetaxel, pemetrexed and carboplatin also show their advantages in radical concurrent chemoradiotherapy.

Key words: Esophageal neoplasms, Radiotherapy, Drug therapy, Capecitabine