国际肿瘤学杂志 ›› 2015, Vol. 42 ›› Issue (6): 469-471.doi: 10.3760/cma.j.issn.1673-422X.2015.06.019

• 综述 • 上一篇    下一篇

樟芝抗肿瘤机制研究进展

陈清法,赵宗杰,谢海涛,张向阳,王鹏亭   

  1. 999077香港中医科学院学术部
  • 收稿日期:2014-09-15 出版日期:2015-06-08 发布日期:2015-05-31
  • 通讯作者: 赵宗杰,Email:1751488915@qq.com E-mail:1751488915@qq.com

Research progress of Antrodia cinnomomea on the anti-hepatocarcinoma mechanism

Chen Qingfa, Zhao Zongjie, Xie Haitao, Zhang Xiangyang, Wang Pengting   

  1. Academic Department, Hong Kong Chinese Medical Science Academy, Hongkong 999077, China
  • Received:2014-09-15 Online:2015-06-08 Published:2015-05-31
  • Contact: Zhao Zongjie E-mail:1751488915@qq.com

摘要: 体外研究表明樟芝具有多个胞内靶点,影响着细胞生长、凋亡、血管新生以及侵袭和迁移。这些靶点包括肿瘤抑制基因、细胞周期调控蛋白、转录因子、血管新生以及迁移因子、凋亡和存活调节剂。此外,樟芝还具有免疫调节特性,可以通过增强免疫力间接地起到抗癌作用。

关键词: 肝肿瘤, 细胞周期, 细胞凋亡, 转录因子, 樟芝

Abstract: Extensive in vitro studies reveal that multiple intracellular targets of Antrodia cinnomomea affect cell growth, apoptosis, angiogenesis, invasion and metastasis. These intracellular targets include tumor suppressor gene, cell cycle regulatory protein, transcription factor, angiogenic and metastatic factors, and apoptotic and survival regulators. In addition, Antrodia cinnomomea has immunomodulatory propertie, which plays an anti-cancer effect indirectly by means of enhancing immunity.

Key words: Liver neoplasms, Cell cycle, Apoptosis, Transcription factors, Antrodia cinnamomea